Pluripotentcells created by reprogramming adult somatic cells and capable of differentiating into:
•Ectoderm-derived tissues(e.g., neurons, skin)
•Mesoderm-derived tissues(e.g., muscle, bone, blood)
•Endoderm-derived tissues(e.g., liver, pancreas, gut)
Key Characteristics
•Unlimited Differentiation Potential: Can give rise to virtually any celltype in the body.
•Cellular Renewal: Capable of extensive proliferation while maintaining pluripotency.
•Reduced Ethical Concerns: Derived from adult cells, circumventingthe ethical issues tied to embryonic stem cells.
•Patient-Specific Therapies: Potentially reduce risk of immunerejection by using the patient’s own cells.
Medical Applications
•Disease Modeling & Research: Generate patient-specific cell lines to study disease mechanisms and testtreatments in vitro.
•Drug Development & Toxicology Screening: Provide human-like cells for early-stage drug testing and toxicity evaluations.
•Regenerative Medicine: Offer potential for repairing damagedtissues (e.g., in cardiac, neurological, or retinal diseases).
•Personalized Therapies: Create tailored treatments for conditions like Parkinson’s disease or diabetesby replacing or repairing malfunctioning cells.