A lysate is a reconstituted mixture derived from cells that have been broken open—much like cracking an egg. Even though the cells are no longer alive, their internal bioactive components remain active. These lysates are rich in cytokines and other molecules that support tissue regeneration, reduce inflammation, and promote anti-aging effects.
Molecules like:
Growth Factors
(Stimulate Regeneration & Repair)
Thesemolecules promote cell growth, differentiation, andextracellular matrix production, making them essential for woundhealing, skin regeneration, and tissue repair.
✅ FibroblastGrowth Factor (FGF) → Stimulates collagen production and tissuerepair.
✅ Epidermal Growth Factor (EGF)→ Enhances skin renewaland cell proliferation.
✅ Transforming Growth Factor-Beta (TGF-β) → Regulates wound healing and cell cycle.
✅ Hepatocyte Growth Factor (HGF)→ Anti-fibrotic, enhances lung and tissue regeneration.
✅ Vascular Endothelial Growth Factor (VEGF)→ Promotes angiogenesis (blood vessel formation)for oxygenation and tissue repair.
✅ Platelet-Derived Growth Factor (PDGF)→ Stimulates fibroblast activationand wound healing.
Cytokines& Anti-Inflammatory Molecules
(Reduce Chronic Inflammation)
Chronicinflammation contributes to aging, lung disease, arthritis, andother degenerative conditions. FE002 lysates contain immunomodulatorymolecules that help control inflammationand reduce immune overactivation.
✅ Interleukin-10(IL-10) → Key anti-inflammatory cytokine, suppresses excessive immune responses.
✅ Tumor Necrosis Factor-alpha (TNF-α) Inhibitors→ Prevents collagen breakdown and chronicinflammation.
✅ Interleukin-6 (IL-6, Regenerative Form)→ Supports tissue repair and neuroprotection.
✅ Colony-Stimulating Factors (G-CSF,GM-CSF) → Promote stem cell activationand immune system regulation.
Antioxidant & DNA Repair Enzymes
(Protect Cells from Aging & Oxidative Stress)
Aging and tissue degeneration are driven by oxidativestress, which damages DNA, proteins, and cell membranes.Our Lysates contain powerful enzymes that neutralize oxidativedamage.
✅ SuperoxideDismutase (SOD) → Converts harmfulfree radicals into non-toxiccompounds.
✅ Glutathione Peroxidase (GPx)→ Prevents DNA damage and oxidative stress.
✅ Catalase (CAT)→ Breaks down hydrogen peroxide, reducing oxidative cell damage.
✅ Heat Shock Proteins (HSPs)→ Protect cells from stress-induced aging.
Extracellular Matrix Proteins
(Hydration & Structural Integrity)
These molecules maintain skin elasticity, hydration, and structure, making them crucial for anti-agingand tissue regeneration.
✅ Collagen(Type I, III, IV, V) → Provides strength and structure to skin, tendons, and organs.
✅ Elastin →Essential for skin and lung elasticity, preventing wrinkles and fibrosis.
✅ Hyaluronic Acid (HA)→ Hydrates and plumps skin, supports joint lubrication.
✅ Laminin & Fibronectin→ Aid cell adhesion, wound healing, and tissue repair.
Exosomes & MicroRNAs
(Regenerate Cells & Reduce Senescence)
Exosomesare nano-vesicles that carry regenerative signals,including proteins, lipids, and microRNAs,which regulate gene expressionand prevent cell aging.
✅ MicroRNA-21& MicroRNA-29 → Rejuvenateaged cells, delay senescence.
✅ ExosomalLipids & Proteins → Support tissuerepair, inflammation control, and immune modulation.
✅ Sirtuin-Activating Compounds (SIRT1,SIRT6) → Promote DNA repair and longevity.
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Medical Applications
Wound Healing & Dermatology
Topical use of lysates supports skin regeneration by stimulating collagen production, enhancing blood vessel formation, and speeding up healing in burns and scars.Anti-
Aging & Skin RejuvenationRich in growth factors, antioxidants, and exosomes, lysates help improve skin firmness, hydration, and elasticity. Key components like FGF, EGF, and collagen fragments aid in reducing wrinkles and repairing sun-damaged skin.
Anti-Senescence Action
Compounds such as microRNAs and sirtuin activators help delay cellular aging and maintain skin vitality.
Inflammation Control & Tissue Repair
Anti-inflammatory cytokines in lysates may reduce chronic inflammation linked to aging, fibrosis, and joint degeneration. Early results show improved healing and lower inflammatory markers.
Pulmonary Applications
Stem cell-derived lysates show potential in regenerating lung tissue, offering promise for conditions like COPD and fibrosis, without the complexity of live-cell therapies.
Neuroprotective Potential
Though still under study, the anti-inflammatory and trophic factors in lysates may support neuron survival and offer new directions for neurodegenerative treatment.
